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Article

Determinants of human cyclin B1 association with mitotic chromosomes.

PloS one - 1 Jan 2013

Pfaff Kathleen L, King Randall W

Abstract excerpt

Cyclin B1-CDK1 activity is essential for mitotic entry, but questions remain regarding how the activity of this kinase is spatially regulated. Previous studies showed that the cyclin B1 subunit localizes to several compartments of a mitotic cell, including the centrosomes, mitotic spindle, kinetochores and chromosomes via distinct sequence elements. Mitotic chromosome association occurs through the unstructured...

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Identifiers

PMID: 23505570
DOI: 10.1371/journal.pone.0059169
PMCID: PMC3594322

Genes

CDK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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