Article
Understanding the Evolutionary Games in NSCLC Microenvironment
2020-11-30
Abstract excerpt
While initially highly successful, targeted therapies eventually fail as populations of tumor cells evolve mechanisms of resistance, leading to resumption of tumor growth. Historically, cell-intrinsic mutational changes have been the major focus of experimental and clinical studies to decipher origins of therapy resistance. While the importance of these mutational changes is undeniable, a growing body of evidence...
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Identifiers and source
- Literature Corpus work
- 3242a2be-a8cc-5df3-82a2-9619a1ff538b
- DOI
- 10.1101/2020.11.30.404350