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Article

Game theory in the death galaxy: interaction of cancer and stromal cells in tumour microenvironment

20 Jun 2014

Abstract excerpt

Preventing relapse is the major challenge to effective therapy in cancer. Within the tumour, stromal (ST) cells play an important role in cancer progression and the emergence of drug resistance. During cancer treatment, the fitness of cancer cells can be enhanced by ST cells because their molecular signalling interaction delays the drug-induced apoptosis of cancer cells. On the other hand, competition among...

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PMID: 25097749
DOI: 10.1098/rsfs.2014.0028

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