Article
Using spatial statistics to infer game-theoretic interactions in an agent-based model of cancer cells
2025-07-15
Abstract excerpt
Drug resistance in cancer is shaped not only by evolutionary processes but also by eco-evolutionary interactions between tumor subpopulations. These interactions can support the persistence of resistant cells even in the absence of treatment, undermining standard aggressive therapies and motivating drug holiday-based approaches that leverage ecological dynamics. A key challenge in implementing such strategies is e...
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Identifiers and source
- Literature Corpus work
- 456317a0-bb4a-53c5-a390-d1644a832d9f
- DOI
- 10.1101/2025.07.09.664005