Article

Characterization of A Bronchoscopically Induced Transgenic Lung Cancer Pig Model for Human Translatability

2024-11-06

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> There remains a need for animal models with human translatability in lung cancer (LC) research. Findings in pigs have high impact on humans due to similar anatomy and physiology. We present the characterization of a bronchoscopically-induced LC model in Oncopigs carrying inducible KRAS G12D and TP53 R167H mutations. <h4>Methods</h4> Twelve Oncopigs underwent 29 injection...

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Literature Corpus work: 30ea8464-fce9-5f8e-a7a8-df6e8a7a690f
DOI: 10.1101/2024.11.04.621940

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