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Article

Biodistribution of Macroaggregated Albumin after Tumor Model Development and Characterization in a Porcine Lung Cancer Model.

Journal of vascular and interventional radiology : JVIR - 1 Nov 2025

Niemeyer Matthew M, Wang Yifan, Carlino Maximillian J, Elkhadragy Lobna, David Odile, Jordan Luke R, Lipnik Andrew J, Blanco Daniel, Mehta Vera, Sambora Evelyn, Schook Lawrence B, Shah Ketan Y, Simpson Russell O, Gaba Ron C, Schachtschneider Kyle M

Abstract excerpt

PURPOSE: To demonstrate that intratracheal infusion of an adenoviral vector carrying Cre recombinase (AdCre) induces lung tumors in the Oncopig and verify that bronchial arterial yttrium-90 transarterial radioembolization (TARE) is the optimal infusion route for lung cancer. MATERIALS AND METHODS: Three transgenic Oncopigs harboring Cre-inducible TP53R167H and KRASG12D mutations underwent tumor induction via...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40803527
DOI: 10.1016/j.jvir.2025.08.007

Genes

KRAS

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