Article
Development and translational imaging of a TP53 porcine tumorigenesis model.
The Journal of clinical investigation - 1 Sept 2014
Sieren Jessica C, Meyerholz David K, Wang Xiao-Jun, Davis Bryan T, Newell John D, Hammond Emily, Rohret Judy A, Rohret Frank A, Struzynski Jason T, Goeken J Adam, Naumann Paul W, Leidinger Mariah R, Taghiyev Agshin, Van Rheeden Richard, Hagen Jussara, Darbro Benjamin W, Quelle Dawn E, Rogers Christopher S
Abstract excerpt
Cancer is the second deadliest disease in the United States, necessitating improvements in tumor diagnosis and treatment. Current model systems of cancer are informative, but translating promising imaging approaches and therapies to clinical practice has been challenging. In particular, the lack of a large-animal model that accurately mimics human cancer has been a major barrier to the development of effective...
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