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Progress towards non-small-cell lung cancer models that represent clinical evolutionary trajectories

1 Jan 2021

Abstract excerpt

Non-small-cell lung cancer (NSCLC) is the leading cause of cancer-related deaths worldwide. Although advances are being made towards earlier detection and the development of impactful targeted therapies and immunotherapies, the 5-year survival of patients with advanced disease is still below 20%. Effective cancer research relies on pre-clinical model systems that accurately reflect the evolutionary course of...

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PMID: 33435818
DOI: 10.1098/rsob.200247

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