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Article

Characterization of A Bronchoscopically Induced Transgenic Lung Cancer Pig Model for Human Translatability

2025-02-03

Abstract excerpt

<title>Abstract</title> <p> Background There remains a need for animal models with human translatability in lung cancer (LC) research. Findings in pigs have high impact on humans due to similar anatomy and physiology. We present the characterization of a bronchoscopically-induced LC model in Oncopigs carrying inducible KRAS <sup>G12D</sup> and TP53 <sup>R167H</sup> mutations. Methods Twelve Oncopigs underw...

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Literature Corpus work
f96a503a-9eb5-5db6-b025-e3443628ec91
DOI
10.21203/rs.3.rs-5054204/v1
Open publication

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Characterization of A Bronchoscopically Induced Transgenic Lung Cancer Pig Model for Human TranslatabilityDOI 10.21203/rs.3.rs-5054204/v1
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