Article

Induction of pancreatic neoplasia in the <i>KRAS</i> / <i>TP53</i> Oncopig

2020-06-02

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Introduction</h4> Five year survival of pancreatic cancer (PC) remains low. Current murine models may not adequately mimic human PC and can be too small for medical device development. A large animal PC model could address these issues. We induced and characterized pancreatic tumors in Oncopigs (transgenic swine with a somatic floxed cassette containing KRAS G12D and TP53 R167H ). <h4>Me...

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Literature Corpus work: a4b34dae-3565-51ab-a7cb-aa7c88d77d03
DOI: 10.1101/2020.05.29.123547

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