Article

Host genetic background is a barrier to broadly effective vaccine protection: Relevance to BCG and <i>Mycobacterium tuberculosis</i> Infection

2022-09-19

Abstract excerpt

<h4>Summary</h4> The heterogeneity of immune responses observed in humans is difficult to model in standard inbred laboratory mice. To capture the diversity inherent in mice and better understand how host variation affects BCG-induced immunity against Mycobacterium tuberculosis , 24 unique Collaborative Cross (CC) recombinant inbred mouse strains and the C57BL/6 reference strain were vaccinated with or without B...

Identifiers and source

Literature Corpus work: 30c84eb0-bdd6-5dff-a788-df602ffd4192
DOI: 10.1101/2022.09.19.508548

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