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Article

Use of mouse models to study the variability in virulence associated with specific genotypic lineages of Mycobacterium tuberculosis.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jun 2012

Hernández-Pando R, Marquina-Castillo B, Barrios-Payán J, Mata-Espinosa D

Abstract excerpt

The host response against Mycobacterium tuberculosis show a wide spectrum of clinical manifestations in those patients who fail to control the infection. The course of the infection and its epidemiological consequences depend upon a complex interplay of host, environmental and bacterial factors. Experimental animal models have helped to define the influence of bacterial genetic diversity on virulence and on the...

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PMID: 22426109
DOI: 10.1016/j.meegid.2012.02.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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