Article

Host-pathogen genetic interactions underlie tuberculosis susceptibility

2020-12-01

Abstract excerpt

The outcome of an encounter with Mycobacterium tuberculosis depends on the pathogen’s ability to adapt to the variable immune pressures exerted by the host. Understanding this interplay has proven difficult, largely because experimentally tractable animal models do not recapitulate the heterogeneity of tuberculosis disease. We leveraged the genetically diverse Collaborative Cross (CC) mouse panel in conjunction w...

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Literature Corpus work: 0acc8188-d1e0-5598-8d91-50c38ddd713e
DOI: 10.1101/2020.12.01.405514

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