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Article

Assessing the potential of polygenic scores to strengthen medical risk prediction models of COVID-19.

PloS one - 1 Jan 2023

Córdova-Palomera Aldo, Siffel Csaba, DeBoever Chris, Wong Emily, Diogo Dorothée, Szalma Sandor

Abstract excerpt

As findings on the epidemiological and genetic risk factors for coronavirus disease-19 (COVID-19) continue to accrue, their joint power and significance for prospective clinical applications remains virtually unexplored. Severity of symptoms in individuals affected by COVID-19 spans a broad spectrum, reflective of heterogeneous host susceptibilities across the population. Here, we assessed the utility of...

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PMID: 37235597
DOI: 10.1371/journal.pone.0285991
PMCID: PMC10218741

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