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A comparative study on the unified model based multifactor dimensionality reduction methods for identifying gene-gene interactions associated with the survival phenotype

2021-02-01

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>For gene-gene interaction analysis, the multifactor dimensionality reduction (MDR) method has been widely employed to reduce multi-levels of gene-gene interactions into high- or low-risk groups using a binary attribute. For the survival phenotype, the Cox-MDR method has been proposed using a martingale residual of a Cox model since Surv-MDR was first proposed us...

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Literature Corpus work: 302148c4-92bb-55cb-9022-a1ca19d43bf7
DOI: 10.21203/rs.3.rs-90733/v2

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