Article
A multifactor dimensionality reduction-logistic regression model of gene polymorphisms and an environmental interaction analysis in cancer research.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2011
Wu Yazhou, Zhang Ling, Liu Ling, Zhang Yanqi, Zhao Zengwei, Liu Xiaoyu, Yi Dong
Abstract excerpt
BACKGROUND: Analysis of interactions between genes and the environment with complex multifactorial human disease faces important challenges. Limitations of parametric-statistical methods for detection of gene effects that are dependent solely or partially on interactions with other genes or environmental exposures are key problems. The aim of the study was to investigate the use of multifactor dimensionality...
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