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Article

Gene-Gene Interaction Analysis for the Survival Phenotype Based on the Kaplan-Meier Median Estimate.

BioMed research international - 1 Jan 2020

Park Mira, Lee Jung Wun, Park Taesung, Lee SeungYeoun

Abstract excerpt

In this study, we propose a simple and computationally efficient method based on the multifactor dimensional reduction algorithm to identify gene-gene interactions associated with the survival phenotype. The proposed method, referred to as KM-MDR, uses the Kaplan-Meier median survival time as a classifier. The KM-MDR method classifies multilocus genotypes into a binary attribute for high- or low-risk groups using...

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Identifiers

PMID: 32461998
DOI: 10.1155/2020/5282345
PMCID: PMC7232685

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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