Article
Gene-gene interaction analysis for the survival phenotype based on the Cox model.
Bioinformatics (Oxford, England) - 15 Sept 2012
Lee Seungyeoun, Kwon Min-Seok, Oh Jung Mi, Park Taesung
Abstract excerpt
MOTIVATION: For the past few decades, many statistical methods in genome-wide association studies (GWAS) have been developed to identify SNP-SNP interactions for case-control studies. However, there has been less work for prospective cohort studies, involving the survival time. Recently, Gui et al. (2011) proposed a novel method, called Surv-MDR, for detecting gene-gene interactions associated with survival time....
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