Article

A <i>Saccharomyces cerevisiae</i> Model for Overexpression of Ntg1 a Base Excision DNA Repair Protein Reveals Novel Genetic Interactions

2022-05-06

Abstract excerpt

<h4>ABSTRACT</h4> The Base Excision Repair (BER) pathway repairs oxidative DNA damage, a common and detrimental form of damage to the genome. Although biochemical steps in BER have been well define, little is understood about how the pathway is regulated. Such regulation is critical, as cells must respond rapidly to DNA damage while avoiding aberrant activation of repair proteins that can produce DNA damage as in...

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Literature Corpus work: 2fa2bace-b41e-5bfa-a937-7d3176e02f54
DOI: 10.1101/2022.05.06.490893

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