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Article

Spontaneous DNA damage in Saccharomyces cerevisiae elicits phenotypic properties similar to cancer cells.

The Journal of biological chemistry - 21 May 2004

Evert Barbara A, Salmon Tiffany B, Song Binwei, Jingjing Liu, Siede Wolfram, Doetsch Paul W

Abstract excerpt

To determine the spectrum of effects elicited by specific levels of spontaneous DNA damage, a series of isogenic Saccharomyces cerevisiae strains defective in base excision repair (BER) and nucleotide excision repair (NER) were analyzed. In log phase of growth, when compared with wild type (WT) or NER-defective cells, BER-defective cells and BER/NER-defective cells possess elevated levels of unrepaired,...

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PMID: 15020594
DOI: 10.1074/jbc.M400468200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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