Article

Transcriptional overlap links DNA hypomethylation with DNA hypermethylation at adjacent promoters in cancer

2021-05-24

Abstract excerpt

<h4>ABSTRACT</h4> DNA methylation is an epigenetic mark associated with gene repression. It is now well established that tumor development involves alterations in DNA methylation patterns, which include both gains (hypermethylation) and losses (hypomethylation) of methylation marks in different genomic regions. The mechanisms underlying these two opposite, yet co-existing, alterations in tumors remain unclear. Wh...

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Literature Corpus work: 2ee6bbeb-39f2-51ea-a5f3-2989d650161e
DOI: 10.1101/2021.05.21.445142

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