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Article

Gains of DNA methylation in myeloid terminal differentiation are dispensable for gene silencing but influence the differentiated phenotype.

The FEBS journal - 1 May 2015

Vento-Tormo Roser, Álvarez-Errico Damiana, Rodríguez-Ubreva Javier, Ballestar Esteban

Abstract excerpt

DNA methylation-mediated regulation drives and stabilizes transcription states throughout development. In myeloid differentiation, DNA methylation changes occur predominantly in the direction towards hypomethylation. Also, in vitro differentiation of monocytes to dendritic cells and macrophages is characterized by DNA demethylation. In this study, we identified the existence of methylation changes in the...

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PMID: 25219924
DOI: 10.1111/febs.13045

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FYN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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