Article

Bridging the Genomic Equity Gap with Context-Enhanced Risk Stratification in American Indians: the Strong Heart Study

2026-02-11

Abstract excerpt

Polygenic scores (PGS) show promise for disease risk stratification but suffer from limited portability across populations. American Indians face a disproportionate burden of cardiovascular disease yet remain significantly underrepresented in genomic research, limiting equitable access to precision medicine. Here, we evaluate whether integrating specific lifestyle and clinical context variables with PGS enhances r...

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Literature Corpus work: 2ea78827-54d1-5dfe-9b6d-4faaedddf5ca
DOI: 10.64898/2026.02.08.26345859

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