Article

Bridging traditional risk factors and genetic insights: A review on polygenic risk scores in cardiovascular diseases

2025-01-01

Abstract excerpt

Cardiovascular diseases (CVDs) remain the leading cause of global morbidity and mortality, with traditional risk models often falling short in predicting individual susceptibility-especially among diverse populations. Recent advances in genomics have led to the development of polygenic risk scores (PRS), which aggregate the effects of multiple single nucleotide polymorphisms (SNPs) to estimate genetic predispositi...

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Literature Corpus work: 5d824f67-c389-58fe-8480-b12cb4bcad71
DOI: 10.1016/j.abst.2025.09.002

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