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Longitudinal investigation of changes in resting-state co-activation patterns and their predictive ability in the zQ175 DN mouse model of Huntington’s disease

2022-12-30

Abstract excerpt

<title>Abstract</title><p>Huntington’s disease (HD) is a neurodegenerative disorder caused by expanded (≥ 40) glutamine-encoding CAG repeats in the huntingtin gene, which leads to dysfunction and death of predominantly striatal and cortical neurons. While the genetic profile and clinical signs and symptoms of the disease are better known, changes in the functional architecture of the brain, especially before the c...

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Literature Corpus work
2e5dce24-cc70-5b9f-a2b3-be787b88d481
DOI
10.21203/rs.3.rs-2405768/v1
Open publication

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Longitudinal investigation of changes in resting-state co-activation patterns and their predictive ability in the zQ175 DN mouse model of Huntington’s diseaseDOI 10.21203/rs.3.rs-2405768/v1
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