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Longitudinal investigation of changes in resting-state co-activation patterns and their predictive ability in the zQ175 DN mouse model of Huntington’s disease

2022-10-09

Abstract excerpt

Huntington’s disease (HD) is a neurodegenerative disorder caused by expanded (≥40) glutamine-encoding CAG repeats in the huntingtin gene, which leads to dysfunction and death of predominantly striatal and cortical neurons. While the genetic profile and behavioural signs of the disease are better known, changes in the functional architecture of the brain, especially before the behavioural symptoms become apparent,...

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Literature Corpus work
2d786e70-7dc7-5e2f-8e93-460dd7ddcbfd
DOI
10.1101/2022.10.09.511485
Open publication

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Longitudinal investigation of changes in resting-state co-activation patterns and their predictive ability in the zQ175 DN mouse model of Huntington’s diseaseDOI 10.1101/2022.10.09.511485
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