Article

Early alterations of motor learning and corticostriatal network activity in a Huntington’s disease mouse model

2024-10-07

Abstract excerpt

<h4>ABSTRACT</h4> Huntington’s disease (HD) is a neurodegenerative disorder that presents motor, cognitive and psychiatric symptoms as it progresses. Prior to motor symptoms onset, alterations and dysfunctions in the corticostriatal projections have been described along with cognitive deficits, but the sequence of early defects of brain circuits is largely unknown. There is thus a crucial need to identify early a...

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Literature Corpus work: a3c551d6-67eb-5fc9-aeec-25ed23a0d987
DOI: 10.1101/2024.10.07.616936

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