Article

Protein complexes in cells by AI-assisted structural proteomics

2022-07-26

Abstract excerpt

<h4>Summary</h4> Accurately modeling the structures of proteins and their complexes using artificial intelligence is revolutionizing molecular biology. Experimental data enables a candidate-based approach to systematically model novel protein assemblies. Here, we use a combination of in-cell crosslinking mass spectrometry, cofractionation mass spectrometry (CoFrac-MS) to identify protein-protein interactions in t...

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Literature Corpus work: 2dcd91a0-005f-54a9-86e3-250345d271c7
DOI: 10.1101/2022.07.26.501605

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