Article

Structural determinants of co-translational protein complex assembly

2024-01-23

Abstract excerpt

<h4>ABSTRACT</h4> The assembly of proteins into functional complexes is critical to life’s processes. While textbooks depict complex assembly as occurring between fully synthesized proteins, we know today that thousands of proteins in the human proteome assemble co-translationally during their synthesis. Why this process takes place, however, remains unknown. We show that co-translational assembly is governed by...

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Literature Corpus work: 65839bcc-a74d-52fa-b657-fbc735676c4f
DOI: 10.1101/2024.01.20.576408

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