Article

hu.MAP 2.0: Integration of over 15,000 proteomic experiments builds a global compendium of human multiprotein assemblies

2020-09-16

Abstract excerpt

A general principle of biology is the self-assembly of proteins into functional complexes. Characterizing their composition is, therefore, required for our understanding of cellular functions. Unfortunately, we lack a comprehensive set of protein complexes for human cells. To address this gap, we developed a machine learning framework to identify protein complexes in over 15,000 mass spectrometry experiments which...

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Literature Corpus work: 70d4eb6e-205d-50a2-85b0-166684864b23
DOI: 10.1101/2020.09.15.298216

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