Article

Accurate Predictions of Liquid-Liquid Phase Separating Proteins at Single Amino Acid Resolution

2024-07-19

Abstract excerpt

Liquid-liquid phase separation (LLPS) is a molecular mechanism that leads to the formation of membraneless organelles inside the cell. Despite recent advances in the experimental probing and computational prediction of proteins involved in this process, the identification of the protein regions driving LLPS and the prediction of the effect of mutations on LLPS are lagging behind. Here, we introduce catGRANULE 2.0...

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Literature Corpus work: 04719cbe-f3c0-5760-9af0-294bfecd3f4e
DOI: 10.1101/2024.07.19.602785

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