Article
The social architecture of an in-depth cellular protein interactome
2021-10-26
Abstract excerpt
Nearly all cellular functions are mediated by protein-protein interactions and mapping the interactome provides fundamental insights into the regulation and structure of biological systems. In principle, affinity purification coupled to mass spectrometry (AP-MS) is an ideal and scalable tool, however, it has been difficult to identify low copy number complexes, membrane complexes and those disturbed by protein-tag...
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Identifiers and source
- Literature Corpus work
- bd07775c-e7ed-526e-a62f-29f825ea9fb5
- DOI
- 10.1101/2021.10.24.465633