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Classification of Single Particles from Human Cell Extract Reveals Distinct Structures

2018-01-14

Abstract excerpt

<h4>Summary</h4> Multi-protein complexes are necessary for nearly all cellular processes, and understanding their structure is required for elucidating their function. Current high-resolution strategies in structural biology are effective, but lag behind other fields (e.g. genomics and proteomics) due to their reliance on purified samples rather than characterizing heterogeneous mixtures. Here, we present a metho...

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Literature Corpus work
d3ceca61-983b-5b36-abee-56be1c30c72b
DOI
10.1101/247254
Open publication

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Classification of Single Particles from Human Cell Extract Reveals Distinct StructuresDOI 10.1101/247254
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