Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The WNT/ROR Pathway in Cancer: From Signaling to Therapeutic Intervention

12 Jan 2021

Abstract excerpt

The WNT pathway is one of the major signaling cascades frequently deregulated in human cancer. While research had initially focused on signal transduction centered on β-catenin as a key effector activating a pro-tumorigenic transcriptional response, nowadays it is known that WNT ligands can also induce a multitude of β-catenin-independent cellular pathways. Traditionally, these comprise WNT/planar cell polarity...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Mechanisms and Therapy
Share to Cancer-related gene regulation
Share to Wnt/β-catenin signaling in development and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33445713
DOI: 10.3390/cells10010142

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The WNT/ROR Pathway in Cancer: From Signaling to Therapeutic InterventionPMID 33445713Read ↗

An update of Wnt signalling in endometrial cancer and its potential as a therapeutic targetSemantic proximity Read ↗

Wnt signaling in cancer: from biomarkers to targeted therapies and clinical translationSemantic proximity Read ↗

The Wnt Signalling Pathway: A Tailored Target in CancerSemantic proximity Read ↗

The Wnt/β-Catenin Signaling Pathway as a Target in Drug DiscoverySemantic proximity Read ↗

Molecular genetics and targeted therapy of WNT-related human diseases (Review).Semantic proximity Read ↗

WNT11 is a novel ligand for ROR2 in human breast cancerSemantic proximity Read ↗

Wnt signaling in cancer.Semantic proximity Read ↗

Ror2 Signaling and Its Relevance in Breast Cancer ProgressionSemantic proximity Read ↗

ROR-Family Receptor Tyrosine Kinases.Semantic proximity Read ↗

The Role of Receptor Tyrosine Kinase-like Orphan Receptor 1 (ROR1) in Cancer Stem Cell SignalingSemantic proximity Read ↗

Targeting the ROR1 and ROR2 receptors in epithelial ovarian cancer inhibits cell migration and invasionSemantic proximity Read ↗

Wnt Signaling and Drug Resistance in Cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.