Article

Nuclear localization and transactivation of SYS-1/β-catenin is the result of serial gene duplications and subfunctionalizations

2021-12-27

Abstract excerpt

β-catenin is a multifunctional protein capable of mediating cell adhesion via E-cadherin and transactivation of target genes of the canonical Wnt signaling pathway. The nematode, C. elegans contains four paralogs of β-catenin which are highly specific in their functions. Though similar in overall structure, the four beta-catenins are functionally distinct, each regulating different aspects of development. Of the...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 82580de9-5ba9-5dc0-8a48-878bae4670e5
DOI: 10.1101/2021.12.26.473689

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Nuclear localization and transactivation of SYS-1/β-catenin is the result of serial gene duplications and subfunctionalizationsDOI 10.1101/2021.12.26.473689Read

Reciprocal asymmetry of SYS-1/β-catenin and POP-1/TCF controls asymmetric divisions in <i>Caenorhabditis elegans</i>Semantic proximity Read

Binary cell fate specification during C. elegans embryogenesis driven by reiterated reciprocal asymmetry of TCF POP-1 and its coactivator beta-catenin SYS-1.Semantic proximity Read

The sys-1 and sys-3 genes cooperate with Wnt signaling to establish the proximal-distal axis of the Caenorhabditis elegans gonad.Semantic proximity Read

Dynamics of a developmental switch: recursive intracellular and intranuclear redistribution of Caenorhabditis elegans POP-1 parallels Wnt-inhibited transcriptional repression.Semantic proximity Read

The Caenorhabditis elegans protein CTBP-1 defines a new group of THAP domain-containing CtBP corepressors.Semantic proximity Read

toca-1 is in a novel pathway that functions in parallel with a SUN-KASH nuclear envelope bridge to move nuclei in Caenorhabditis elegans.Semantic proximity Read

POP-1 controls axis formation during early gonadogenesis in C. elegans.Semantic proximity Read

Suppressors of zyg-1 define regulators of centrosome duplication and nuclear association in Caenorhabditis elegans.Semantic proximity Read

C. elegans CPB-3 interacts with DAZ-1 and functions in multiple steps of germline developmentSemantic proximity Read

Crosstalk between a nuclear receptor and beta-catenin signaling decides cell fates in the C. elegans somatic gonad.Semantic proximity Read

DYC-1, a protein functionally linked to dystrophin in Caenorhabditis elegans is associated with the dense body, where it interacts with the muscle LIM domain protein ZYX-1.Semantic proximity Read

A nuclear function for armadillo/beta-catenin.Semantic proximity Read