Article

Disrupted role of the connectivity between the locus coeruleus and the hippocampus in cognition of healthy, middle-aged individuals at risk of dementia: the PREVENT-Dementia study

2022-09-02

Abstract excerpt

It is well acknowledged that Alzheimer’s Disease (AD) pathological processes start decades before clinical manifestations, but the brain mechanism of sporadic AD in midlife remains unclear. To address this gap, we examined whether risk factors for late-life AD are associated with disrupted connectivity between two key structures in AD pathophysiology – the Locus Coeruleus (LC) and hippocampus – and its role in cog...

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Literature Corpus work: 2cfe0851-b6c9-5bb8-a191-d4a3f132719c
DOI: 10.1101/2022.09.02.22279541

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Disrupted role of the connectivity between the locus coeruleus and the hippocampus in cognition of healthy, middle-aged individuals at risk of dementia: the PREVENT-Dementia studyDOI 10.1101/2022.09.02.22279541Read

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