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Article

Apolipoprotein E genotype, gender and age modulate connectivity of the hippocampus in healthy adults.

NeuroImage - 1 Sept 2014

Heise Verena, Filippini Nicola, Trachtenberg Aaron J, Suri Sana, Ebmeier Klaus P, Mackay Clare E

Abstract excerpt

Important risk factors for Alzheimer's disease (AD) are ageing and the Apolipoprotein E (APOE) ε4 allele, with female APOE ε4 carriers having the greatest risk. In this study we investigated effects of AD risk factors on connectivity of the hippocampus, a structure that shows early AD related pathology. Resting-state functional magnetic resonance imaging and diffusion tensor imaging data from 86 cognitively...

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Source

Identifiers

PMID: 24814213
DOI: 10.1016/j.neuroimage.2014.04.081

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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