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Article

The midlife cognitive profiles of adults at high risk of late-onset Alzheimer's disease: The PREVENT study.

Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Oct 2017

Ritchie Karen, Carrière Isabelle, Su Li, O'Brien John T, Lovestone Simon, Wells Katie, Ritchie Craig W

Abstract excerpt

INTRODUCTION: Although biomarker studies of late-onset Alzheimer's disease suggest pathology to be present decades before diagnosis, little is known about cognitive performance at this stage. METHODS: A sample of 210 adults (aged 40-59) of whom 103 have a parent diagnosed with dementia (family history subgroup) underwent computerized cognitive testing. Apolipoprotein E (apoE) status was determined, and 193...

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PMID: 28365321
DOI: 10.1016/j.jalz.2017.02.008

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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