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Article

Elucidating the mechanisms of transcription regulation during heart development by next-generation sequencing.

Journal of human genetics - 1 Jan 2016

Nimura Keisuke, Kaneda Yasufumi

Abstract excerpt

Dysregulation of transcription is associated with the pathogenesis of cardiovascular diseases, including congenital heart diseases and heart failure. However, it remains unclear how transcription factors regulate transcription in the heart and which genes are associated with cardiovascular diseases in humans. Development of genome-wide analyses using next-generation sequencers provides powerful methods to...

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Identifiers

PMID: 26202577
DOI: 10.1038/jhg.2015.84

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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