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Article

ConDoR: tumor phylogeny inference with a copy-number constrained mutation loss model.

Genome biology - 30 Nov 2023

Sashittal Palash, Zhang Haochen, Iacobuzio-Donahue Christine A, Raphael Benjamin J

Abstract excerpt

A tumor contains a diverse collection of somatic mutations that reflect its past evolutionary history and that range in scale from single nucleotide variants (SNVs) to large-scale copy-number aberrations (CNAs). However, no current single-cell DNA sequencing (scDNA-seq) technology produces accurate measurements of both SNVs and CNAs, complicating the inference of tumor phylogenies. We introduce a new evolutionary...

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Identifiers

PMID: 38037115
DOI: 10.1186/s13059-023-03106-5
PMCID: PMC10688497

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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