Article

Differing lymphokine profiles of functional subsets of human CD4 and CD8 T cell clones

1991-10-11

Abstract excerpt

Functional subsets of human T cells were delineated by analyzing patterns of lymphokines produced by clones from individuals with leprosy and by T cell clones of known function. CD4 clones from individuals with strong cell-mediated immunity produced predominantly interferon-gamma, whereas those clones that enhanced antibody formation produced interleukin-4. CD8 cytotoxic T cells secreted interferon-gamma. Interleu...

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Literature Corpus work: 2b23e078-ea89-5e7e-b3cc-c9a4e22cd243
DOI: 10.1126/science.254.5029.279

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