Article

Defining protective responses to pathogens: cytokine profiles in leprosy lesions

1991-10-11

Abstract excerpt

The immunological mechanisms required to engender resistance have been defined in few infectious diseases of man, and the role of specific cytokines is unclear. Leprosy presents clinically as a spectrum in which resistance correlates with cell-mediated immunity to the pathogen. To assess in situ cytokine patterns, messenger RNA extracted from leprosy skin biopsy specimens was amplified by the polymerase chain reac...

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Literature Corpus work: ac3fb6f5-120d-5e4c-953c-e568a27dcedd
DOI: 10.1126/science.254.5029.277

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