Article
Differing Lymphokine Profiles of Functional Subsets of Human CD4 and CD8 T Cell Clones
11 Oct 1991
Abstract excerpt
Functional subsets of human T cells were delineated by analyzing patterns of lymphokines produced by clones from individuals with leprosy and by T cell clones of known function. CD4 clones from individuals with strong cell-mediated immunity produced predominantly interferon-gamma, whereas those clones that enhanced antibody formation produced interleukin-4. CD8 cytotoxic T cells secreted interferon-gamma....
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