Article
Phenotype and suppressor activity of T-lymphocyte clones extracted from lesions of oral lichen planus.
The British journal of dermatology - 1 Sept 1994
Sugerman P B, Savage N W, Seymour G J
Abstract excerpt
Lymphocytes were extracted from six biopsy specimens of oral lichen planus. T-lymphocyte lines were expanded in culture with phytohaemagglutinin and interleukin 2, and cloned by limiting dilution. Fifteen T-cell clones were isolated with a probability of clonality of 96.3%. The majority of clones...
Topics
- Adult
- Aged
- CD4-Positive T-Lymphocytes
- CD8-Positive T-Lymphocytes
- Female
- Humans
- Lichen Planus, Oral
- Lymphocyte Activation
- Middle Aged
- Phenotype
- Receptors, Antigen, T-Cell, alpha-beta
- Receptors, Antigen, T-Cell, gamma-delta