Article
Phenotype and suppressor activity of T-lymphocyte clones extracted from lesions of oral lichen planus.
The British journal of dermatology - 1 Sept 1994
Sugerman P B, Savage N W, Seymour G J
Abstract excerpt
Lymphocytes were extracted from six biopsy specimens of oral lichen planus. T-lymphocyte lines were expanded in culture with phytohaemagglutinin and interleukin 2, and cloned by limiting dilution. Fifteen T-cell clones were isolated with a probability of clonality of 96.3%. The majority of clones (n = 13) expressed the alpha beta T-cell receptor, and of these, 11 were CD8+ and two were CD4+. Two clones were CD4-...
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