Article
Phenotypic and functional heterogeneity of human T cell clones producing gamma-interferon.
La Ricerca in clinica e in laboratorio - 1 Jan 2000
Melioli G, Merli A, Ferrini S, Mingari M C, Moretta L
Abstract excerpt
Human T cell clones were derived from peripheral blood and screened for their ability to release gamma-interferon (gamma-IF) following PHA stimulation. Nine clones producing more than 20 U/ml of gamma-IF were expanded and analyzed for cytolytic activity in a lectin-dependent assay and for the ability to release interleukin-2 (IL-2). In addition, clones were analyzed for T4 and T8 antigen expression. Five out of...
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