Article

Revealing the Drivers Underlying Distinct Evolutionary Trajectories in Lung Adenocarcinoma

2025-12-23

Abstract excerpt

Elucidating the evolution of cancers allows us to understand their key events, and the order in which they occur. To chart and interpret these evolutionary trajectories, we leverage whole-genome sequencing of lung tumours, including those from the largest cohort to date of lung cancers in subjects who have never smoked. Through ordering frequent genomic alterations, we discover three distinct evolutionary paths ta...

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Literature Corpus work: 2a4f74f1-64be-548e-9004-ed7a275e359e
DOI: 10.64898/2025.12.19.695410

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