Article

Panorama of Chromosomal Instability in Lung Cancer

2025-09-12

Abstract excerpt

Lung cancer is a highly heterogeneous disease primarily driven by tobacco smoking. About 20% of lung cancers occur among patients who have never smoked (LCINS) with differences in patient ancestry, sex, tumor histology, and clinical features. Our understanding of chromosomal instability in lung cancer, especially LCINS, is still limited. Here, we perform a comprehensive study of 182,429 somatic structural variatio...

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Literature Corpus work: 92abdeaa-cf1a-5baa-ada6-be8fff6e7616
DOI: 10.1101/2025.09.09.25335109

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