Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Revealing the subtyping of non-small cell lung cancer based on genomic evolutionary patterns by multi-region sequencing.

Cancer medicine - 1 Dec 2020

Liao Gaoming, Liang Xin, Ping Yanyan, Zhang Yong, Liao Jianlong, Wang Yihan, Hou Xiaobo, Jiang Zedong, Dong Xiaoqiu, Xu Chaohan, Xiao Yun

Abstract excerpt

Accurately classifying patients with non-small cell lung cancer (NSCLC) from the perspective of tumor evolution has not been systematically studied to date. Here, we reconstructed phylogenetic relationships of somatic mutations in 100 early NSCLC patients (327 lesions) through reanalyzing the TRACERx data. Based on the genomic evolutionary patterns presented on the phylogenetic trees, we grouped NSCLC patients...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Non-Small-Cell Lung
Share to Clonal Evolution

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Computational Biology

Share to Databases, Genetic

Share to Genomics

Share to High-Throughput Nucleotide Sequencing

Share to Lung Neoplasms

Share to Survival Rate

Source

Open in PubMed Open full text

Identifiers

PMID: 33078899
DOI: 10.1002/cam4.3541
PMCID: PMC7774747

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Revealing the subtyping of non-small cell lung cancer based on genomic evolutionary patterns by multi-region sequencing.PMID 33078899Read ↗

Revealing the Drivers Underlying Distinct Evolutionary Trajectories in Lung AdenocarcinomaSemantic proximity Read ↗

Tumor evolutionary trajectories during the acquisition of invasiveness in early stage lung adenocarcinoma.Semantic proximity Read ↗

Phylogenetic and phylodynamic approaches to understanding the evolution of non-small cell lung cancer using single-cell sequencingSemantic proximity Read ↗

Genetic Clonality as the Hallmark Driving Evolution of Non-Small Cell Lung CancerSemantic proximity Read ↗

Intratumor heterogeneity comparison among different subtypes of non-small-cell lung cancer through multi-region tissue and matched ctDNA sequencingSemantic proximity Read ↗

Circulating tumor DNA analysis depicts subclonal architecture and genomic evolution of small cell lung cancer.Semantic proximity Read ↗

The evolution of lung cancer and impact of subclonal selection in TRACERx.Semantic proximity Read ↗

Tracking Genomic Cancer Evolution for Precision Medicine: The Lung TRACERx StudySemantic proximity Read ↗

Phylomedicine of mutational processes in somatic cancer cell populationsSemantic proximity Read ↗

Evolution of small cell lung cancer tumor mutation: from molecular mechanisms to novel viewpoints.Semantic proximity Read ↗

Spatial and temporal diversity in genomic instability processes defines lung cancer evolution.Semantic proximity Read ↗

Comprehensive Characterization of Somatic Mutation Timing Reveals the Evolutionary Trajectory of Lung Adenocarcinoma in Chinese Patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.