Article
Genetic Alterations in Preinvasive Lung Synchronous Lesions.
Cancer research and treatment - 1 Oct 2020
Ahn Soyeon, Lim Jisun, Park Soo Young, Kim Hyojin, Kwon Hyun Jung, Han Yeon Bi, Lee Choon-Taek, Cho Sukki, Chung Jin-Haeng
Abstract excerpt
PURPOSE: Despite advances in treatment, lung cancer remains the leading cause of cancer mortality. This study aimed to characterise genome-wide tumorigenesis events and to understand the hypothesis of the multistep carcinogenesis of lung adenocarcinoma (LUAD). MATERIALS AND METHODS: We conducted multiregion whole-exome sequencing of LUAD with synchronous atypical adenomatous hyperplasia (AAH), adenocarcinoma in...
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