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A SuperSelective primer-based real-time PCR platform for hypersensitive detection of azole heteroresistance in <i>Cryptococcus neoformans</i>

2026-04-24

Abstract excerpt

Cryptococcus neoformans is the leading cause of fungal meningitis with limited treatment options, making early and accurate diagnosis critical for improved patient outcome. Current diagnostic methods for cryptococcosis rely largely on capsule antigen detection and fungal culture, which are time-consuming and unable to identify mutation-driven antifungal heteroresistance. In this study, we have developed a SuperSel...

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Literature Corpus work
29f2ec14-9475-5ff9-9f99-0ba02507685c
DOI
10.64898/2026.04.23.720376
Open publication

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A SuperSelective primer-based real-time PCR platform for hypersensitive detection of azole heteroresistance in <i>Cryptococcus neoformans</i>DOI 10.64898/2026.04.23.720376
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